Multi-Purpose Functional Materials Based on Thermosensitive Poly (N-vinylcaprolactam)

Studies on Thermosensitive Poly(N-vinylcaprolactam) Based Polymers for Pharmaceutical Applications

....................................................................................................................................... iii List of original publications .............................................................................................. vi Abbreviations and symbols .............................................................................................. vii Ackn...

Development of Multi-Purpose Biological Reference Materials

Thermoresponsive poly(N-vinylcaprolactam) as stationary phase for aqueous and green liquid chromatography

Poly(N-vinylcaprolactam) (PVCL) connected to aminopropyl silica is a new stationary phase for temperature responsive liquid chromatography (TR-LC). PVCL shows a transition from hydrophilic to hydrophobic interaction between 30 and 40°C. The synthesis is described in detail. The temperature responsive characteristic of the phase is illustrated with a mixture of steroids using pure water as mobil...

Tuning assembly and enzymatic degradation of silk/poly(N-vinylcaprolactam) multilayers via molecular weight and hydrophobicity.

We report on enzymatically degradable nanothin coatings obtained by layer-by-layer (LbL) assembly of silk fibroin with poly(N-vinylcaprolactam) (PVCL) via hydrogen bonding and hydrophobic interactions. We found that both silk β-sheet content, controlled through dipping and spin-assisted LbL, and PVCL molecular weight regulate film thickness, microstructure, pH-stability, and biodegradability wi...

Thermally Sensitive and Biocompatible Poly(N-vinylcaprolactam): Synthesis and Characterization of High Molar Mass Linear Chains

High molar mass poly(N-vinylcaprolactam) (PVCa) was synthesized by free-radical bulk polymerization. Four narrowly distributed fractions of PVCa were obtained in the tetrahydrofuran/nhexane mixture. A combination of static and dynamic laser light scattering led to a scaling between the translational diffusion coefficient (D) and molar mass (M), D (cm2/s) ) 8.47 × 10Mw, with which we transferred...